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Calculate allele and genotype frequencies in populations
p (dominant)
0.6000
q (recessive)
0.4000
p + q = 1.0000
AA (p²)
36.00%
360 individuals
Aa (2pq)
48.00%
480 individuals
aa (q²)
16.00%
160 individuals
Hardy-Weinberg Equation
p² + 2pq + q² = 1
0.3600 + 0.4800 + 0.1600 = 1.0000
Hardy-Weinberg predicts genetic equilibrium when 5 conditions are met
Real populations never perfectly meet HW assumptions - evolution is always occurring
Genetic drift violates HW by changing allele frequencies randomly
Gene flow (migration) introduces new alleles, disrupting equilibrium
Natural selection favors certain alleles, shifting genotype frequencies
HW is like a null hypothesis - deviations indicate evolutionary forces
The equation can estimate carrier frequencies for recessive diseases
HW helps forensic scientists calculate expected DNA profile frequencies